• Users Online: 145
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
BRIEF REPORT
Year : 2016  |  Volume : 2  |  Issue : 1  |  Page : 24-27

Successful use of cyclosporine in the treatment of toxic epidermal necrolysis: A case series


1 Consultant Dermatologist, Midaz Heights, Central Bazar Road, Ramdaspeth, Nagpur, Maharashtra, India
2 Consultant Pediatrician, Getwel Hospital, Dhantoli, Nagpur, Maharashtra, India
3 Department of Dermatology, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India

Correspondence Address:
Vikrant Saoji
Consultant Dermatologist, Ramdaspeth, Nagpur, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2455-3972.184089

Rights and Permissions

Toxic epidermal necrolysis (TEN) is an acute life-threatening disease associated with a high mortality. Systemic corticosteroids, cyclosporine, and intravenous gamma globulins have been used in the treatment with variable results. We report five cases of TEN treated successfully with cyclosporine monotherapy. All the patients presented with severe disease. All the patients received cyclosporine 3–5 mg/kg/day for an average duration of 5–10 days depending on the clinical response. All the patients recovered without any sequel. No significant side effects were noted in all the five patients except for one patient who developed acute nephrotoxicity. All the five patients were discharged from the hospital by the end of 2 weeks, thus decreasing the hospital stay due to a favorable outcome and early recovery. Cyclosporine in TEN patients is not only a lifesaving drug, but also it is cost-effective. This case series demonstrates the safety and efficacy of the short course of cyclosporine monotherapy in the treatment of TEN.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2382    
    Printed67    
    Emailed0    
    PDF Downloaded147    
    Comments [Add]    

Recommend this journal