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Year : 2019  |  Volume : 5  |  Issue : 2  |  Page : 107-109

D-penicillamine-induced elastosis perforans serpiginosa in a case of Wilson's disease

1 Department of Dermatology, Venereology and Leprosy, Seth G.S. Medical College and KEM Hospital, Mumbai, Maharashtra, India
2 Department of Gastroenterology, Jaslok Hospital, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Shefali Saini
Room No. 905, UG/PG Hostel, Seth G.S. Medical College and KEM Hospital, Parel, Mumbai - 400 012, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijdd.ijdd_53_19

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The use of D-penicillamine has been well established in various disorders, mainly Wilson's disease, cystinuria, and rheumatoid arthritis. Elastosis perforans serpiginosa (EPS) is a rare perforating dermatosis, occurring as an uncommon sequel of long-term high-dose D-penicillamine therapy. We present a rare case of EPS in a known case of Wilson's Disease on D-penicillamine therapy. Biopsy revealed characteristic “lumpy-bumpy” elastic fibers, a finding specific to penicillamine-induced EPS.

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