Indian Journal of Drugs in Dermatology

MANAGING A SIDE EFFECT
Year
: 2020  |  Volume : 6  |  Issue : 1  |  Page : 49--52

Cardiac side effect of rituximab


Vaibhav Bansidhar Patil1, Snehal Balvant Lunge2, Bhavana Ravindra Doshi2 
1 Department of Cardiology, Venereology and Leprosy, J. N. Medical College, Belagavi, Karnataka, India
2 Department of Dermatology, Venereology and Leprosy, J. N. Medical College, Belagavi, Karnataka, India

Correspondence Address:
Dr. Snehal Balvant Lunge
Assistant Professor, Department of Dermatology, Venereology and Leprosy, J. N. Medical College, Belagavi - 590 010, Karnataka
India

Rituximab is an anti-CD20 monoclonal antibody frequently used for the treatment of non-Hodgkin's lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, and anti-neutrophilic cytoplasmic antibody-associated vasculitis. In addition, rituximab has recently been increasingly used as an off-label treatment in a number of inflammatory and systemic autoimmune diseases. Its side effect profile includes infusion-related reactions and adverse cardiac effects such as arrhythmia and angina, particularly in patients with prior history of cardiovascular diseases. However, its detailed cardiotoxicity profile, effects on cardiac function, and its management are not well described in the literature. As the utility of rituximab expands, primary physicians, intensivist, dermatologist who use drug should be made of these serious cardiovascular adverse effect.


How to cite this article:
Patil VB, Lunge SB, Doshi BR. Cardiac side effect of rituximab.Indian J Drugs Dermatol 2020;6:49-52


How to cite this URL:
Patil VB, Lunge SB, Doshi BR. Cardiac side effect of rituximab. Indian J Drugs Dermatol [serial online] 2020 [cited 2020 Aug 9 ];6:49-52
Available from: http://www.ijdd.in/article.asp?issn=2455-3972;year=2020;volume=6;issue=1;spage=49;epage=52;aulast=Patil;type=0