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Year : 2018  |  Volume : 4  |  Issue : 1  |  Page : 26-28

Peculiar acral and oral pigmentation after docetaxel therapy: An unresolved dilemma

Department of Dermatology, Venereology and Leprosy, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India

Correspondence Address:
Dr. Guneet Awal
H. No. 469, East Mohan Nagar, Opposite DSP Park, Sultan Wind Road, Amritsar - 143 001, Punjab
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijdd.ijdd_9_18

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Taxanes, which are widely used chemotherapeutic agents for treating breast carcinoma, are known to cause various cutaneous side effects with incidence as high as 65%. These cutaneous manifestations range from minor nonspecific dermatological manifestations to perplexing atypical manifestations of classic entities such as hand-foot syndrome. We report a case of 51-year-old previously healthy postmenopausal woman diagnosed with T1N1M0 adenocarcinoma breast, on docetaxel adjuvant chemotherapy, who developed peculiar oral and acral violaceous hyperpigmentation. Recognition of this type of presentation as part of HFS or a separate entity is still a debatable conundrum.

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