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Year : 2021  |  Volume : 7  |  Issue : 2  |  Page : 67-71

Comparative clinical assessment of 5% minoxidil topical application with supplemental intradermal meso-solution administration for the management of androgenetic alopecia in men

1 Department of Dermatology, Venerology and Leperology, NSCB Government Medical College & Hospital, Jabalpur, Madhya Pradesh, India
2 Jabalpur Hospital & Research Centre, Jabalpur, Madhya Pradesh, India

Correspondence Address:
Neha Gupta
Department of Dermatology, Venerology and Leperology, NSCB Government Medical College & Hospital, Jabalpur, Madhya Pradesh.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijdd.ijdd_15_20

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Objectives: Androgenetic alopecia (AGA) is characterized by progressive patterned hair loss from the scalp affecting both men and women. The aim of this study was to evaluate the influence of intradermal administration of meso-solution (MS) along with topical application of 5% minoxidil lotion on hair re-growth. Materials and Methods: Sixty healthy adult men (32.6 ± 4.3 years of age) with a history of hair loss completed the 12-month study. They were equally randomized into two groups. Subjects enrolled in Group A (n1 = 30) received once-daily topical application of 5% minoxidil lotion, whereas those in Group B (n2 = 30) received additional intradermal injection of MS (Stem C’rum HL, Caregen Co. Ltd, Anyang-si, Gyeonggi-do, South Korea) using a mesogun every 15 days for 3 months and then once every month for 9 months. Hair re-growth was evaluated using a 7-point rating scale. Results: Data collected were subjected to chi-square test. Results indicate that there is a statistically significant (P < 0.05) increase in hair re-growth in individuals in Group B at 6 months. This progressed to a highly significant (P < 0.001) increase at 9 and 12 months. Conclusion: Intradermal administration of MS using a mesogun along with minoxidil yielded a statistically significant increase in hair re-growth as compared to only minoxidil application.

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